2023

System level immune monitoring reveals new pathophysiological features in hepatitis-associated aplastic anemia. Braudeau C, Delbos L, Couec MC, Danic G, Chevreuil J, Lecuroux C, Grain A, Eveillard M, Rialland F, Sicre de Font Brune F, Beriou G, Degauque N, Michonneau D, Josien R, Peffault de La Tour R, Thomas C, Martin JC. Blood Advances, in press.

Lien: https://pubmed.ncbi.nlm.nih.gov/37267438/

First-in-Human Study in Healthy Subjects with the Noncytotoxic Monoclonal Antibody OSE-127, a Strict Antagonist of IL-7Rα. Poirier N, Baccelli I, Belarif L, Abès R, Teppaz G, Mary C, Poli S, Fromond C, Girault I, Pengam S, Soma E, De Sa F, Conduzorgues JP, Braudeau C, Josien R, Volckaert B, Costantini D, Corallo F. J Immunol. 2023 Feb 3:ji2200635. doi: 10.4049/jimmunol.2200635. Online ahead of print. PMID: 36734626.

Lien: https://pubmed.ncbi.nlm.nih.gov/36734626/

2022

IL-22BP production is heterogeneously distributed in Crohn's disease. Fantou A, Lagrue E, Laurent T, Delbos L, Blandin S, Jarry A, Beriou G, Braudeau C, Salabert N, Marin E, Moreau A, Podevin J, Bourreille A, Josien R, Martin JC. Front Immunol. 2022 Oct 13;13:1034570. doi: 10.3389/fimmu.2022.1034570. eCollection 2022.

Lien: https://pubmed.ncbi.nlm.nih.gov/36311796/

A Phase I/IIa study of autologous tolerogenic dendritic cells immunotherapy in kidney transplant recipients. Moreau A, Kervella D, Bouchet-Delbos L, Braudeau C, Saïagh S, Guérif P, Limou S, Moreau A, Bercegeay S, Streitz M, Sawitzki B, James B, Harden PN, Game D, Tang Q, Markmann JF, Roberts ISD, Geissler EK, Dréno B, Josien R, Cuturi MC, Blancho G; DIVAT consortium. Kidney Int. 2022 Oct 26:S0085-2538(22)00845-6. doi: 10.1016/j.kint.2022.08.037. Online ahead of print.

Lien : https://pubmed.ncbi.nlm.nih.gov/36306921/

Antibody-mediated allograft rejection is associated with an increase in peripheral differentiated CD28-CD8+ T cells – Analyses of a cohort of 1032 kidney transplant recipients. Mai HL, Degauque N, Le Bot S, Rimbert M, Renaudin K, Danger R, Le Borgne F, Kerleau C, Tilly G, Vivet A, Delbos F, Walencik A, Giral M, Brouard S. EBioMedicine. 2022 Aug 18;83:104226. doi: 10.1016/j.ebiom.2022.104226. Online ahead of print.

Lien: https://pubmed.ncbi.nlm.nih.gov/35988467/

Neutralizing Anti-Granulocyte Macrophage-Colony Stimulating Factor Autoantibodies Recognize Post-Translational Glycosylations on Granulocyte Macrophage-Colony Stimulating Factor Years Before Diagnosis and Predict Complicated Crohn's Disease. Mortha A, Remark R, Del Valle DM, Chuang LS, Chai Z, Alves I, Azevedo C, Gaifem J, Martin J, Petralia F, Tuballes K, Barcessat V, Tai SL, Huang HH, Laface I, Jerez YA, Boschetti G, Villaverde N, Wang MD, Korie UM, Murray J, Choung RS, Sato T, Laird RM, Plevy S, Rahman A, Torres J, Porter C, Riddle MS, Kenigsberg E, Pinho SS, Cho JH, Merad M, Colombel JF, Gnjatic S. Gastroenterology. 2022 Sep;163(3):659-670. doi: 10.1053/j.gastro.2022.05.029. Epub 2022 May 24.

Lien: https://pubmed.ncbi.nlm.nih.gov/35623454/

Monocyte Signature Associated with Herpes Simplex Virus Reactivation and Neurological Recovery after Brain Injury. Chaumette T, Cinotti R, Mollé A, Solomon P, Castain L, Fourgeux C, McWilliam HEG, Misme-Aucouturier B, Broquet A, Jacqueline C, Vourc'h M, Fradin D, Bossard C, David L, Montassier E, Braudeau C, Josien R, Villadangos JA, Asehnoune K, Bressollette-Bodin C, Poschmann J, Roquilly A. Am J Respir Crit Care Med. 2022 Aug 1;206(3):295-310. doi: 10.1164/rccm.202110-2324OC.

Lien: https://pubmed.ncbi.nlm.nih.gov/35486851/

Transfusion-Related Renal Dysfunction After Cardiac Surgery: The Role of Myeloid-Related Protein_14 in Neutrophil-Mediated Tubular Damage. Vourc'h M, Roquilly A, Foucher A, Retiere C, Feuillet F, Devi S, McWilliam HEG, Braudeau C, Bourreille G, Hachani A, O'Kane D, Mueller SN, Ischia J, Roussel JC, Rigal JC, Josien R, Rozec B, Villadangos JA, Asehnoune K. JACC Basic Transl Sci. 2022 Jun 1;7(7):627-638. doi: 10.1016/j.jacbts.2022.02.019. eCollection 2022 Jul.

Lien: https://pubmed.ncbi.nlm.nih.gov/35958696/

Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity. Uzzan M, Martin JC, Mesin L, Livanos AE, Castro-Dopico T, Huang R, Petralia F, Magri G, Kumar S, Zhao Q, Rosenstein AK, Tokuyama M, Sharma K, Ungaro R, Kosoy R, Jha D, Fischer J, Singh H, Keir ME, Ramamoorthi N, Gorman WEO, Cohen BL, Rahman A, Cossarini F, Seki A, Leyre L, Vaquero ST, Gurunathan S, Grasset EK, Losic B, Dubinsky M, Greenstein AJ, Gottlieb Z, Legnani P, George J, Irizar H, Stojmirovic A, Brodmerkel C, Kasarkis A, Sands BE, Furtado G, Lira SA, Tuong ZK, Ko HM, Cerutti A, Elson CO, Clatworthy MR, Merad M, Suárez-Fariñas M, Argmann C, Hackney JA, Victora GD, Randolph GJ, Kenigsberg E, Colombel JF, Mehandru S. Nat Med. 2022 Feb 21. doi: 10.1038/s41591-022-01680-y. Online ahead of print.

Lien: https://pubmed.ncbi.nlm.nih.gov/35190725/

2021

Pharmacokinetics and Safety of XAV-19, a Swine Glyco-humanized Polyclonal Anti-SARS-CoV-2 Antibody, for COVID-19-Related Moderate Pneumonia: a Randomized, Double-Blind, Placebo-Controlled, Phase IIa Study. Gaborit B, Dailly E, Vanhove B, Josien R, Lacombe K, Dubee V, Ferre V, Brouard S, Ader F, Vibet MA, Le Thuaut A, Danger R, Flet L, Omnes A, Berly L, Chiffoleau A, Jobert A, Duvaux O, Raffi F; POLYCOR Trial Group. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0123721. doi: 10.1128/AAC.01237-21. Epub 2021 Aug 17.

Lien: https://pubmed.ncbi.nlm.nih.gov/34181475/

Monocytic Human Leukocyte Antigen DR Expression in Young Infants Undergoing Cardiopulmonary Bypass. Chenouard A, Rimbert M, Joram N, Braudeau C, Roquilly A, Bourgoin P, Asehnoune K; ImmunoPed Group. Ann Thorac Surg. 2021 May;111(5):1636-1642. doi: 10.1016/j.athoracsur.2020.05.071. Epub 2020 Jul 8.

Lien: https://pubmed.ncbi.nlm.nih.gov/32652073/

Evaluation of the safety and efficacy of XAV-19 in patients with COVID-19-induced moderate pneumonia: study protocol for a randomized, double-blinded, placebo-controlled phase 2 (2a and 2b) trial. Gaborit B, Vanhove B, Vibet MA, Le Thuaut A, Lacombe K, Dubee V, Ader F, Ferre V, Vicaut E, Orain J, Le Bras M, Omnes A, Berly L, Jobert A, Morineau-Le Houssine P, Botturi K, Josien R, Flet L, Degauque N, Brouard S, Duvaux O, Poinas A, Raffi F; POLYCOR study group. Trials. 2021 Mar 9;22(1):199. doi: 10.1186/s13063-021-05132-9.

Lien: https://pubmed.ncbi.nlm.nih.gov/33750432/

Preformed T cell alloimmunity and HLA eplet mismatch to guide immunosuppression minimization with tacrolimus monotherapy in kidney transplantation: Results of the CELLIMIN trial. Bestard O, Meneghini M, Crespo E, Bemelman F, Koch M, Volk HD, Viklicky O, Giral M, Banas B, Ruiz JC, Melilli E, Hu L, van Duivenvoorden R, Nashan B, Thaiss F, Otto NM, Bold G, Stein M, Sefrin A, Lachmann N, Hruba P, Stranavova L, Brouard S, Braudeau C, Blancho G, Banas M, Irure J, Christakoudi S, Sanchez-Fueyo A, Wood KJ, Reinke P, Grinyó JM. Am J Transplant. 2021 Mar 16. doi: 10.1111/ajt.16563. Online ahead of print.

Lien: https://pubmed.ncbi.nlm.nih.gov/33725408/

Non-permissive human conventional CD1c+ dendritic cells enable trans-infection of human primary renal tubular epithelial cells and protect BK polyomavirus from neutralization. Sikorski M, Coulon F, Peltier C, Braudeau C, Garcia A, Giraud M, Renaudin K, Kandel-Aznar C, Nedellec S, Hulin P, Branchereau J, Véziers J, Gaboriaud P, Touzé A, Burlaud-Gaillard J, Josien R, McIlroy D, Bressollette-Bodin C, Halary F. PLoS Pathog. 2021 Feb 16;17(2):e1009042. doi: 10.1371/journal.ppat.1009042. eCollection 2021 Feb.

Lien: https://pubmed.ncbi.nlm.nih.gov/33592065/

An easy and reliable whole blood freezing method for flow cytometry immuno-phenotyping and functional analyses. Braudeau C, Salabert-Le Guen N, Chevreuil J, Rimbert M, Martin JC, Josien R. Cytometry B Clin Cytom. 2021 Feb 5. doi: 10.1002/cyto.b.21994. Online ahead of print.PMID: 33544978 

Lien: https://pubmed.ncbi.nlm.nih.gov/33544978/

Concomitant decrease of double-positive lymphocyte population CD4CD8αα and Faecalibacterium prausnitzii in patients with colorectal cancer. Touchefeu Y, Duchalais E, Bruley des Varannes S, Alameddine J, Mirallie E, Matysiak-Budnik T, Le Bastard Q, Javaudin F, Rimbert M, Jotereau F, Montassier E. Eur J Gastroenterol Hepatol. 2021 Feb 1;32(2):149-156. doi: 10.1097/MEG.0000000000001842.PMID: 32675782

Lien: https://pubmed.ncbi.nlm.nih.gov/32675782/

2020

PD-1 and TIGIT coexpression identifies a circulating CD8 T cell subset predictive of response to anti-PD-1 therapy. Simon S, Voillet V, Vignard V, Wu Z, Dabrowski C, Jouand N, Beauvais T, Khammari A, Braudeau C, Josien R, Adotevi O, Laheurte C, Aubin F, Nardin C, Rulli S, Gottardo R, Ramchurren N, Cheever M, Fling SP, Church CD, Nghiem P, Dreno B, Riddell SR, Labarriere N. J Immunother Cancer. 2020 Nov;8(2):e001631. doi: 10.1136/jitc-2020-001631.

Lien: https://pubmed.ncbi.nlm.nih.gov/33188038/

Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function. Gruber CN, Calis JJA, Buta S, Evrony G, Martin JC, Uhl SA, Caron R, Jarchin L, Dunkin D, Phelps R, Webb BD, Saland JM, Merad M, Orange JS, Mace EM, Rosenberg BR, Gelb BD, Bogunovic D. Immunity. 2020 Sep 15;53(3):672-684.e11. doi: 10.1016/j.immuni.2020.07.006. Epub 2020 Aug 3.PMID: 32750333

Lien: https://pubmed.ncbi.nlm.nih.gov/32750333/

Why is SARS-CoV-2 infection more severe in obese men? The gut lymphatics - Lung axis hypothesis. Uzzan M, Corcos O, Martin JC, Treton X, Bouhnik Y. Med Hypotheses. 2020 Nov;144:110023. doi: 10.1016/j.mehy.2020.110023. Epub 2020 Jun 23. PMID: 32593832

Lien: https://pubmed.ncbi.nlm.nih.gov/32593832/

Transient antibody targeting of CD45RC inhibits the development of graft-versus-host disease. Boucault L, Lopez Robles MD, Thiolat A, Bézie S, Schmueck-Henneresse M, Braudeau C, Vimond N, Freuchet A, Autrusseau E, Charlotte F, Redjoul R, Beckerich F, Leclerc M, Piaggio E, Josien R, Volk HD, Maury S, Cohen JL, Anegon I, Guillonneau C. Blood Adv. 2020 Jun 9;4(11):2501-2515. doi: 10.1182/bloodadvances.2020001688. PMID:32511714

Lien: https://pubmed.ncbi.nlm.nih.gov/32511714/

Regulatory Cell Therapy in Kidney Transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials. Sawitzki B, Harden PN, Reinke P, Moreau A, Hutchinson JA, Game DS, Tang Q, Guinan EC, Battaglia M, Burlingham WJ, Roberts ISD, Streitz M, Josien R, Böger CA, Scotta C, Markmann JF, Hester JL, Juerchott K, Braudeau C, James B, Contreras-Ruiz L, van der Net JB, Bergler T, Caldara R, Petchey W, Edinger M, Dupas N, Kapinsky M, Mutzbauer I, Otto NM, Öllinger R, Hernandez-Fuentes MP, Issa F, Ahrens N, Meyenberg C, Karitzky S, Kunzendorf U, Knechtle SJ, Grinyo J, Morris PJ, Brent L, Bushell A, Turka LA, Bluestone JA, Lechler RI, Schlitt HJ, Cuturi MC, Schlickeiser S, Friend PJ, Miloud T, Scheffold A, Secchi A, Crisalli K, Kang SM, Hilton R, Banas B, Blancho G, Volk HD, Lombardi G, Wood KJ, Geissler EK. Lancet. 2020 May 23;395(10237):1627-1639. doi: 10.1016/S0140-6736(20)30167-7. 

Lien: https://pubmed.ncbi.nlm.nih.gov/32446407/

Preclinical assessment of Autologous Tolerogenic Dendritic Cells from End-stage renal disease patients. Bouchet-Delbos L, Even A, Varey E, Saïagh S, Bercegeay S, Braudeau C, Dréno B, Blancho G, Josien R, Cuturi MC, Moreau A. Transplantation. 2020 May 15. doi: 10.1097/TP.0000000000003315. [Epub ahead of print]  PMID:32433241

Lien: https://pubmed.ncbi.nlm.nih.gov/32433241/ 

Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages. Merad M, Martin JC. Nat Rev Immunol. 2020 Jun;20(6):355-362. doi: 10.1038/s41577-020-0331-4. Epub 2020 May 6.PMID: 32376901

Lien : https://pubmed.ncbi.nlm.nih.gov/32376901/

2019

Immunophenotyping of a rat model of Duchenne’s disease and demonstration of improved muscle strength after anti-CD45RC antibody treatment. Ouisse LH, Remy S, Lafoux A, Larcher T, Tesson L, Chenouard V, Guillonneau C, Brusselle L, Vimond N, Rouger K, Pereon Y, Chenouard A, Gras-Le Guen C, Braudeau C, Josien R, Huchet C, Anegon I. Front Immunol. 2019 Sep 9;10:2131. doi: 10.3389/fimmu.2019.02131. eCollection 2019

Lien: https://pubmed.ncbi.nlm.nih.gov/31552055/

IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease. Belarif L, Danger R, Kermarrec L, Nerrière-Daguin V, Pengam S, Durand T, Mary C, Kerdreux E, Gauttier V, Kucik A, Thepenier V, Martin JC, Chang C, Rahman A, Guen NS, Braudeau C, Abidi A, David G, Malard F, Takoudju C, Martinet B, Gérard N, Neveu I, Neunlist M, Coron E, MacDonald TT, Desreumaux P, Mai HL, Le Bas-Bernardet S, Mosnier JF, Merad M, Josien R, Brouard S, Soulillou JP, Blancho G, Bourreille A, Naveilhan P, Vanhove B, Poirier N. J Clin Invest. 2019 Apr 2; 130. pii: 121668. doi: 10.1172/JCI121668.

Lien: https://pubmed.ncbi.nlm.nih.gov/30939120/

2018

B cell depletion therapy dampens CD8+ T cells response in ANCA-associated vasculitis. Néel A, Bucchia M, Néel M, Tilly G, Caristan A, Yap M, Rimbert M, Bruneau S, Cadoux M, Agard C, Hourmant M, Godmer P, Brouard S, Bressollette C, Hamidou M, Josien R, Fakhouri F, Degauque N. Arthritis & Rheumatology. 2018 Oct 30 doi: 10.1002/art.40766  [Epub ahead of print] PMID: 30375745

Lien: https://pubmed.ncbi.nlm.nih.gov/30375745/

A standardized flow cytometry procedure for the monitoring of regulatory T cells in clinical trials. Pitoiset F, Barbié M, Monneret G, Braudeau C, Pochard P, Pellegrin I, Trauet J, Labalette M, Klatzmann D, Rosenzwajg M. Cytometry B Clin Cytom. 2018 Jan 6. doi: 10.1002/cyto.b.21622. [Epub ahead of print] PMID: 29316248

Lien: https://pubmed.ncbi.nlm.nih.gov/29316248/

HLA-DR expression in neonates after cardiac surgery under cardiopulmonary bypass: a pilot study. Chenouard A, Braudeau C, Cottron N, Bourgoin P, Salabert N, Roquilly A, Josien R, Joram N, Asehnoune K. Intensive Care Med Exp. 2018 Jan 11;6(1):1. doi: 10.1186/s40635-017-0166-x. PMID: 29327145

Lien: https://pubmed.ncbi.nlm.nih.gov/29327145/

2017

Bronchiectasis is highly prevalent in anti-MPO ANCA-associated vasculitis and is associated with a distinct disease presentation. Néel A, Espitia-Thibault A, Arrigoni PP, Volteau C, Rimbert M, Masseau A, Agard C, Fakhouri F, Liberge R, Hamidou M. Semin Arthritis Rheum. 2017 Dec 7. pii: S0049-0172(17)30586-3. doi: 10.1016/j.semarthrit.2017.12.002. [Epub ahead of print] PMID: 29336783

Lien: https://pubmed.ncbi.nlm.nih.gov/29336783/

Thymic stromal lymphopoietin does not activate human basophils. Salabert-Le Guen N, Hémont C, Delbove A, Poli C, Braudeau C, Fantou A, Amouriaux K, Bériou G, Martin JC, Colas L, Soumelis V, Josien R. J Allergy Clin Immunol. 2017 Dec 5. pii: S0091-6749(17)31876-6. doi: 10.1016/j.jaci.2017.11.012. [Epub ahead of print]  PMID: 29208546

Lien: https://pubmed.ncbi.nlm.nih.gov/29208546/

Standardized whole blood stimulation improves immunomonitoring of induced immune responses in multi-center study. Duffy D, Rouilly V, Braudeau C, Corbière V, Djebali R, Ungeheuer MN, Josien R, LaBrie S, Lantz O, Louis D, Martinez-Caceres E, Mascart F, Ruiz de Morales JG, Ottone C, Redjah L, Guen NS, Savenay A, Schmolz M, Toubert A, Albert ML; Multinational FOCIS Centers of Excellence. Clin Immunol. 2017 Oct;183:325-335. doi: 10.1016/j.clim.2017.09.019. Epub 2017 Sep 22. PMID: 28943400

Lien: https://pubmed.ncbi.nlm.nih.gov/28943400/

Local Modulation of Antigen-Presenting Cell Development after Resolution of Pneumonia Induces Long-Term Susceptibility to Secondary Infections. Roquilly A, McWilliam HEG, Jacqueline C, Tian Z, Cinotti R, Rimbert M, Wakim L, Caminschi I, Lahoud MH, Belz GT, Kallies A, Mintern JD, Asehnoune K, Villadangos JA. Immunity. 2017 Jul 18;47(1):135-147.e5. doi: 10.1016/j.immuni.2017.06.021. PMID: 28723546

Lien: https://pubmed.ncbi.nlm.nih.gov/28723546/

Is Pre-transplant sensitization against Angiotensin II Type1 Receptor still a risk factor of graft and patient outcome in kidney transplantation in the anti HLA Luminex era? Deltombe C, Gillaizeau F, Anglicheau D, Morelon E, Trébern-Launay K, Le Borgne F, Rimbert M, Guérif P, Malard-Castagnet S, Foucher Y, Giral M. Transpl Int. 2017 Nov;30(11):1150-1160. doi: 10.1111/tri.13009. Epub 2017 Oct 5. PMID: 28686316

Lien : https://pubmed.ncbi.nlm.nih.gov/28686316/

Cell-surface C-type lectin-like receptor CLEC-1 dampens dendritic cell activation and downstream Th17 responses. Lopez Robles MD, Pallier A, Huchet V, Le Texier L, Remy S, Braudeau C, Delbos L, Moreau A, Louvet C, Brosseau C, Royer PJ, Magnan A, Halary F, Josien R, Cuturi MC, Anegon I, Chiffoleau E. Blood Adv. 2017 Mar 22;1(9):557-568. doi: 10.1182/bloodadvances.2016002360. eCollection 2017 Mar 28. PMID: 29296975

Lien : https://pubmed.ncbi.nlm.nih.gov/29296975/

Dysregulated responsiveness of circulating dendritic cells to Toll-like receptors in ANCA-associated vasculitis. Braudeau C, Neel A, Amouriaux K, Martin JC, Rimbert M, Besancon A, Giraudet S, Terrien C, Aliaga M, Salabert-Le Guen N, Hemont C, Hamidou M, Josien R. Front. Immunol 2017. 8:102. doi: 10.3389/fimmu.2017.00102. PMID: 28232832

Lien : https://pubmed.ncbi.nlm.nih.gov/28232832/

2016

First-in-Human Study in Healthy Subjects with FR104, a Pegylated Monoclonal Antibody Fragment Antagonist of CD28. Poirier N, Blancho G, Hiance M, Mary C, Van Assche T, Lempoels J, Ramael S, Wang W, Thepenier V, Braudeau C, Salabert N, Josien R, Anderson I, Gourley I, Soulillou JP, Coquoz D, Vanhove B. J Immunol. 2016 Dec 15;197(12):4593-4602. Epub 2016 Nov 14  PMID:29316248

Lien : https://pubmed.ncbi.nlm.nih.gov/27849166/

Persistent deficiency of circulating mucosal-associated invariant T (MAIT) cells in ANCA-associated vasculitis. Braudeau C, Amouriaux K, Néel A, Herbreteau G, Salabert N, Rimbert M, Martin JC, Hémont C, Hamidou M, Josien R. J Autoimmun. 2016 Jun;70:73-9. doi: 10.1016/j.jaut.2016.03.015. Epub 2016 Apr 18 PMID: 27102145

Lien : https://pubmed.ncbi.nlm.nih.gov/27102145/

2015

Receptor activating NF-kB ligand (RANKL) is a constitutive intracellular protein in resting human basophils and is strongly induced on their surface by interleukine 3. Poli C, Martin JC, Braudeau C, Beriou G, Hémont C, Charrier C, Guerin S, Heslan M, Josien R. Immunobiology. 2015 May;220(5):692-700. doi: 10.1016/j.imbio.2014.11.009. Epub 2014 Nov 21. PMID: 25433635

Lien: https://pubmed.ncbi.nlm.nih.gov/25433635/

Involvement of the CXCL1 (fractalkine)/CXCR1 pathway in the pathogenesis of acute graft-versus-host disease. Brissot E, Bossard C, Malard F, Braudeau C, Chevallier P, Guillaume T, Delaunay J, Josien R, Gregoire M, Gaugler B, Mohty M. J Leukoc Biol. 2015 Feb;97(2):227-35. doi: 10.1189/jlb.5HI0714-325R. Epub 2014 Nov 24. PMID: 25420917

Lien : https://pubmed.ncbi.nlm.nih.gov/25420917/

2014

Hydrocortisone prevents immunosuppression by interleukine-10+ natural killer cells after trauma-hemorrhage. Roquilly A, Broquet A, Jacqueline C, Masson D, Segain JP, Braudeau C, Vourc’h M, Caillon J, Altare F, Josien R, Retiere C, Villadangos J, Ashenoune K. Crit Care Med. 2014 Dec;42(12):e752-61. doi: 10.1097/CCM.0000000000000658. PMID: 25289930

Lien : https://pubmed.ncbi.nlm.nih.gov/25289930/

2013

Impaired blood dendritic cell numbers and functions after aneurysmal subarachnoid hemorrhage. Braudeau C*, Roquilly A*, Cinotti R, Dumontet E, Motreul R, Josien R, Ashenoune K. PLoS One. 2013 Aug 9;8(8):e71639. doi: 10.1371/journal.pone.0071639. eCollection 2013. PMID: 23951210

Lien : https://pubmed.ncbi.nlm.nih.gov/23951210/

Altered innate function of plasmacytoid dendritic cells restored by enzyme replacement therapy in Gaucher disease. Braudeau C*, Graveleau J*, Rimbert M, Néel A, Hamidou M, Grosbois B, Besançon A, Giraudet S, Terrien C, Josien R and Masseau A. Blood Cells Mol Dis. 2013 Apr;50(4):281-8. doi: 10.1016/j.bcmd.2013.01.001. Epub 2013 Jan 26. PMID : 23357793

Lien : https://pubmed.ncbi.nlm.nih.gov/23357793/

Human blood myeloid dendritic cell subsets exhibit distinct TLR repertoire and responsiveness. Hemont C, Néel A, Heslan M, Braudeau C, Josien R. J Leukoc Biol. 2013 Apr;93(4):599-609. doi: 10.1189/jlb.0912452. Epub 2013 Jan 22. PMID: 23341538

Lien : https://pubmed.ncbi.nlm.nih.gov/23341538/

2011

Decreased numbers of blood dendritic cells and defective function of regulatory T cells in antineutrophil cytoplasmic antibody-associated vasculitis. Rimbert M, Hamidou M, Braudeau C, Puéchal X, Teixeira L, Caillon H, Néel A, Audrain M, Guillevin L, Josien R. PLoS One. 2011 Apr 8;6(4):e18734. doi: 10.1371/journal.pone.0018734. PMID: 2149463

Lien: https://pubmed.ncbi.nlm.nih.gov/21494636/

2010

Results of a phase I study in patients suffering from secondary-progressive multiple sclerosis demonstrating the safety of the amino acid copolymer PI-2301 and a possible induction of an anti-inflammatory cytokine response. Kovalchin J, Krieger J, Genova M, Collins K, Augustyniak M, Masci A, Hittinger T, Kuca B, Edan G, Braudeau C, Rimbert M, Patel U, Mascioli E, Zanelli E. J Neuroimmunol. 2010 Aug 25;225(1-2):153-63. doi: 10.1016/j.jneuroim.2010.04.008. Epub 2010 May 13. PMID: 20466440

Lien : https://pubmed.ncbi.nlm.nih.gov/20466440/